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The Emerging Threat of Drug Resistant Tuberculosis

dc.contributor.authorAcademy of Science of South Africa (ASSAf)
dc.date.accessioned2017-05-31T13:58:30Z
dc.date.available2017-05-31T13:58:30Z
dc.date.issued2011
dc.identifier.citationAcademy of Science of South Africa (ASSAf), (2011). The Emerging Threat of Drug Resistant Tuberculosis. [Online] Available at: DOI http://dx.doi.org/10.17159/assaf/0013en_ZA
dc.identifier.isbn978-0-309-16024-7
dc.identifier.isbn0-309-16024-3
dc.identifier.otherhttp://dx.doi.org/10.17159/assaf/0013
dc.identifier.urihttp://hdl.handle.net/20.500.11911/55
dc.descriptionCite: Academy of Science of South Africa (ASSAf), (2011). The Emerging Threat of Drug Resistant Tuberculosis. [Online] Available at: DOI http://dx.doi.org/10.17159/assaf/0013en_ZA
dc.description.abstractAn estimated 2 billion people, one-third of the global population, are infected with Mycobacterium tuberculosis (M.tb.), the bacterium that causes tuberculosis (TB) (Keshavjee and Seung, 2008). Spread through the air, this infectious disease kills 1.8 million people each year, or 4,500 each day (WHO, 2009a). TB is the leading killer of people with HIV, and it is also a disease of poverty—the vast majority of TB deaths occur in the developing world (WHO, 2009a). Exacerbating the devastation caused by TB is the growing threat of drug-resistant strains of the disease in many parts of the world. The development of drug resistance is a predictable, natural phenomenon that occurs when microbes adapt to survive in the presence of drug therapy (Nugent et al., 2010). Although antibiotics developed in the 1950s are effective against a large percentage of TB cases, resistance to these first-line therapies has developed over the years, resulting in the growing emergence of multidrug-resistant (MDR) and extensively drugresistant (XDR) TB, and even totally drug-resistant (TDR) TB (see Box 1-1 for definitions). In recognitionen_ZA
dc.description.sponsorshipUS Academy of Sciencesen_ZA
dc.language.isoenen_ZA
dc.publisherAcademy of Science of South Africaen_ZA
dc.subjectMycobacterium tuberculosis (M.tb.)en_ZA
dc.subjectMultidrug-resistant (MDR)en_ZA
dc.subjectExtensively drugresistant (XDR)en_ZA
dc.subjectTotally drug-resistant (TDR)en_ZA
dc.subjectSustainable Development Goals (SDGs)
dc.subjectSDG 2
dc.subjectSDG 3
dc.subjectSDG 6
dc.subjectSDG 9
dc.subjectSDG 11
dc.subjectSDG 16
dc.titleThe Emerging Threat of Drug Resistant Tuberculosisen_ZA
dc.typeWorkshop Proceedingsen_ZA
dc.identifier.doi10.17159/assaf/0013
assaf.peer-review.statusNon-Peer Reviewed


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